药学院课题组网站

2020

16. Min Xi, Yizhou Li*, and Jiang Zhou*, Exploration of the formation and structure characteristics of a miR-92a promoter G-quadruplex by ESI-MS and CD. Talanta. 2020, 211: 120708.

10.1016/j.talanta.2019.120708

 

 

2019

15. Guixian Zhao, Yiran Huang, Yu Zhou, Yizhou Li*, and Xiaoyu Li*, Future challenges with DNA-encoded chemical libraries in the drug discovery domain, Expert Opinion on Drug Discovery, 2019, 14(8): 735-753.

10.1080/17460441.2019.1614559

2018

14. Yizhou Li*, Roberto De Luca, Samuele Cazzamalli, Francesca Pretto, Davor Bajic, Jörg Scheuemann*, and Dario Neri*, Versatile protein recognition by the encoded display of multiple chemical elements on a constant macrocyclic scaffold, Nature Chemistry, 2018. 10(4), 441-448.

10.1038/s41557-018-0017-8

 

2017

13. Yizhou Li, Gunther Zimmermann, Jörg Scheuemann, and Dario Neri*, Quantitative PCR is a Valuable Tool to Monitor the Performance of DNA-Encoded Chemical Library Selections, ChemBioChem. 2017. 18, 848-852.

 10.1002/cbic.201600626           ·  Selected as the issue’s back cover       

12. Gunther Zimmermann, Yizhou Li, Jörg Scheuemann, and Dario Neri*, Hit-Validation Methodologies for Ligands Isolated from DNA-Encoded Chemical Libraries, ChemBioChem. 2017. 18, 853-857.

10.1002/cbic.201600637

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2016

11. Yizhou Li, Elena Gabriele, Florent Samain, Nicholas Favalli, Filippo Sladojevich, Jörg Scheuemann, and Dario Neri*, Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries, ACS Comb. Sci. 2016. 18, 438-443. 

10.1021/acscombsci.6b00058

 

2015

10. Xinping Chen, Chunyue Zhao, Xiaolong Li, Tao Wang, Yizhou Li, Cheng Cao, Yuehe Ding, Mengqiu Dong, Lorenzo Finci, Jia-huai Wang,* Xiaoyu Li* and Lei Liu*, Li* and Lei Liu* ,Terazosin activated Pgk1 and Hsp90 to promote stress resistance, Nat. Chem. Biol. 2015, 11, 19-25.

10.1038/nchembio.1657

 

2014

9. Peng Zhao, Zitian Chen, Yizhou Li, Dawei Sun, Yuan Gao, Yanyi Huang* and Xiaoyu Li*, Selection of DNA-encoded small molecule libraries against unmodified and non-immobilized protein targets, Angew. Chem. Int. Ed. 2014, 53, 10056-10059.

10.1002/anie.201404830         ·  Selected as “hot paper” and the issue's front co

2013

8. Yizhou Li, Peng Zhao,Mingda Zhang, Xianyuan Zhao, and Xiaoyu Li*, Multistep DNA-templated synthesis using a universal template, J. Am. Chem. Soc. 2013, 135, 1772717730.

10.1021/ja409936r                  ·  Highlighted by “JACS Spotlights”

 

2012

7. Yizhou Li, Mingda Zhang, Chi Zhang, and Xiaoyu Li*, Detection of bond formations by DNA-programmed chemical reactions and PCR amplification, Chem. Commun., 2012, 48, 9513-9515.

10.1039/C2CC35230C

Graphical abstract: Detection of bond formations by DNA-programmed chemical reactions and PCR amplification

6. Chi Zhang, Yizhou Li, Mingda Zhang, and Xiaoyu Li*, DNA-directed formation of peptide bond: a model study towards DNA-programmed peptide ligation, Tetrahedron, 2012, 68, 5152-5156.

10.1016/j.tet.2012.04.032

2010

5. Yizhou Li, Zheng Zhu and Xiaoyu Li*, Drug Discovery by DNA Programming in New Frontiers in Chemical Biology: Enabling Drug Discovery, Royal Society of Chemistry Drug Discovery Series, 2010, ISBN-10: 184973125X, pp 257-301.

 

2009

4. Yizhou Li, Bijie Li, XingYu Lu, Song Lin, and Zhangjie Shi*, Cross Dehydrogenative Arylation (CDA) of a Benzylic C-H Bond with Arenes by Iron Catalysis, Angew. Chem. Intl. Ed. Eng. 2009, 48, 3817-3820.

10.1002/anie.200900341           ·  Selected as "hot paper"

2008

3. Bijie Li, Yizhou Li, Xingyu Lu, Jia Liu, Bingtao Guan, and Zhangjie Shi*, Cross-Coupling of Aryl/Alkenyl Pivalates with Organozinc Reagents through Nickel-Catalyzed C-O Bond Activation under Mild Reaction Conditions, Angew. Chem. Intl. Ed. Eng. 2008, 47, 10124-10127.

10.1002/anie.200803814

2. Shangdong Yang, Changliang Sun, Zhao Fang, Bijie Li, Yizhou Li, and Zhangjie Shi*, Palladium-Catalyzed Direct Arylation of (Hetero)Arenes with Aryl Boronic Acids, Angew. Chem. Intl. Ed. Eng. 2008, 47, 1473-1476.

10.1002/anie.200704619

2007

1. Guixin Cai, Ye Fu, Yizhou Li, Xiaobing Wan, and Zhangjie Shi*, Indirect ortho Functionalization of Substituted Toluenes through ortho Olefination of N, N-Dimethylbenzylamines Tuned by the Acidity of Reaction Conditions, J. Am. Chem. Soc. 2007, 129, 7666-7673. 

10.1021/ja070588a